04/2005- 2006 Research Specialist, University of
Baltimore Medical School, Department of Medicine, Division of
Rheumatology/Immunology, 10 S Pine St, Baltimore, MD 21201.
04/2004 -2005 Research Specialist , University of
Massachusetts Medical School, Department of
Medicine, Division of Infectious Diseases, Lazare Research
Building, 364 Plantation street, Worcester, MA 01655.
2001-2003Research
Instructor, University of North Carolina at Chapel Hill, School of Medicine. Department of Cell and Molecular Physiology, Chapel Hill, North Carolina 27599.
1986 - 2000 Asssistant Professor, Department
of Medicine University of Arkansas for Medical Sciences, Little Rock,
Arkansas 72205
1982 - 2000 Research Chemist, Veterans
Administration Medical Center, Little Rock. Arkansas 72205.
1980 - 1981 Research Associate, Department of
Biochemistry, Temple University School of Medicine,
Philadelphia, PA 19140.
1978 - 1980 Research Associate, Department of
Chemistry, Tulane
University, New Orleans, Louisiana 70118.
Honors and Awards:
- American Medical Association Scholarships (1973-1975).
- Graduate Research Assistantship (1975-1978).
- Performance Award (VA) (1986-1987, 1990-1991).
- Oustanding Rating Certificate (VA) (1987-1988).
- Outstanding Performance Award (VA) (1989-1990).
Brief Past and Current Research Grant Applications
(Agencies & Dates):
American Institute for Cancer Research : “ Effects of
high fat diets on eicosanoid synthesis and tumorigenesis in prostate
cancer” Principle Investigator (1998-2000, pending), submited 12/8/97.
Department of Defense Prostate Cancer Research Program:
“Cytokine-Induced Enzyme Markers In Prostate Cancer” (1998-2001).
Co-Investigator. VA RAG: "Arachidonic Acid Deficiency in Prostatic
Cancer Rats". Co-Investigator (1993-1995, funded); NIH: "Biomarkers in
Prostate Cancer". Co-Investigator (1995-1998, funded); VA Merit Review:
"Dietary and Hormonal Regulation of Fatty Acid Desaturase in Diabetic
Rats". Principle Investigator. June 1993; VA RAG:
"Prostatic-Carcinoma-Derived Growth Factors". Principle Investigator.
Submitted January 1993; VA Merit Review: "Effects of Fish Oil
supplemented diet on blood glucose control of diabetes. Co-Investigator.
1992.
Professional Members:
Member (1994-2000): Arkansas Cancer Research Center
(ACRC). 4301 W. MarkhamLittle Rock, AR 72205.
Member (1985-1997): American Association for the
Advancement of Sciences
1333 H
Street N.W.
Washington, D.C. 20005
Member (1987-1990): American Oil Chemists' Society1608 Broadmore DriveChampaign, Il 61821
Member (1986-1989): American Federation for Clinical
Research 6900 Grove Road Thorofare, New Jersey 08086
.
Alternate Member: VA Medical Research Animal
Care and Use Committee (1992-2000)
(ACUC).
PUBLICATIONS:
A. Abstracts:
1.- Dang AQ, Cook DE: Metabolism of the sulfur-containing
amino acids in Tetrahymena pyriformis. 19th West Central States
Biochemical Conference, 1976.
2.- Dang AQ, Cook DE: Inhibition effects of itaconic acid
on glyconeogenesis in Tetrahymena pyriformis, strain E. Federation
Proceedings 37: 1479, 1978.
3.- Dang AQ, Faas FH, Carter WJ: Reduced hepatic
microsomal long-chain Acyl-CoA synthetase and long-chain acyl-CoA
hydrolase activities in the streptozotocin diabetic rat. 74 Annual
Meeting of the American Society of Biological Chemists. Federation
Proceedings 42: 1 858, 1983.
4.- Faas FH, Dang AQ, Carter WJ: Effects of
streptozotocin diabetes on fatty acyl-CoA glycerophospholipid acyl
transferase in the diabetic rat liver. 55th Annual Meeting of the
Endocrine Society. June 1983.
5.- Dang AQ, Faas FH, Carter WJ: Alterations of
phospholipid metabolism in the diabetic rat. VIIth International
Congress of Endocrinology, Quebec City, Canada, July 1984.
6.- Faas FH, Dang AQ, Carter WJ: Regulation of rat liver
glycerophospholipid fatty acid composition in hypo- and hyperthyroidism.
9th International Thyroid Congress. Sao Paulo, Brasil, September 1985.
7.- Dang AQ, Faas FH, Carter Wj: Effects of hypo- and
hyperthyroidism on rat liver microsomal long-chain fatty acyl-CoA
synthetase and hydrolase. Federation Proceedings 45: 1484, 1986.
8.- Dang AQ, Faas FH: Altered fatty acid composition in
the plasma lipids from streptozotocin-induced diabetic rats. Federation
Proceedings 46:2178, 1987.
9.- Faas FH, Dang AQ, Kemp K, Norman J, Carter: Red Blood
Cell (RBC) fatty acid composition in diabetes. Diabetes 36 (suppl
1):195A, 1987.
10.- Faas FH, Dang AQ, Lee JA, Carter WJ: Altered fatty
acid composition in vascular tissues in the diabetic rat. Presented at
the 8th International Congress of Endocrinology, July 17-23, 1988,
Kyoto, Japan.
11.- Taylor BJ, Sziszak TL, Sziszak TJ,
Walker RG, Dang AQ: Effects of hypoxia on the pulmonary circulation,
lung mechanics and thromboxane production before and after cromolyn
sodium and U-60, 257. The Society for Pediatric Research, 1989.
12.- Lehman PA, Franz TJ, Dang AQ: Effects of acute
diabetes and insulin therapy on stratium corneum barrier function in
rats. Society for Investigative Dermatology, 52nd Annual Meeting, May
1-3, 1991. Seattle, Washington.
13.- Jethmalani SM, Dang AQ, Faas FH: Phosphoinositide
turnover and platelet hyperactivation in streptozotocin-induced
diabetes. 9th International Congress of Endocrinology,
August30-September 5, 1992. Nice, France.
14.- Dang AQ, Liem PH, Faas FH, Jethmalani SM, Moix FM,
Carter WJ: Lipid composition and membrane fluidity of red blood cell and
platelet from Alzheimer's, multi-infarct dementia, healthy young and old
subjects. FASEB J 7(7). Abstract # 1259, April 20, 1993
15.- Faas FH, Dang AQ, Hong XM, Schutz M, Luckert PH,
Pollard M: Increased phospholipid fatty acid turnover through
acylation-deacylation pathways in malignant prostatic tissues: 1995
Annual Meeting, American Urological Association, Inc. Las Vegas, NV.
16.- Dang AQ, Faas FH, Mehta R, White J, Dang TM: The
characteristics of lysolecithin acyltransferase in human prostate
tissues. 89 th Annual Meeting of the American Association for Cancer
Research. March 28-April 1, 1998. New Orleans, LA. Abstract # 803.
17. An Q. Dang, Zhangping Peng, and William J.
Arendshorst. The Relative Abundance of Phospholipase C Isoforms In
Renal Cortical Microcirculation. Abstract presented to the Department
of Cell and Molecular Physiology, University of North Carolina at Chapel
Hill Research Day, August 15, 2002.
B. Published Articles:
1.- Dang AQ, Cook DE: The Transsulfuration pathway in
Tetrahymena pyriformis. Biochim Biophys Acta 486: 264-271, 1977.
2.- Dang AQ, Cook DE: Itaconic acid: An inhibitor of
isocitrate lyase in Tetrahymena pyriformis in-vitro and
in-vivo. Biochim Biophys Acta 678: 312-316, 1981.
3.- Doetsch PW, Suhadolnik RJ, Sawada Y, Mosca JD, Flick
MB, Reichenbach NL, Dang AQ, Wu JM, Charuba R, Pfleidereer W, Henderson
EE: Core (2'-5') oligoadenylate and cordycepin analog: inhibitors of
Epstein-Bar virus-induced transformation of human lymphocytes in the
absence of interferon. Proc Natl Acad Sci USA 78: 6699-6703, 1981.
4.- Ikejima M, Sawada Y, Dang AQ, Suhadolnik
RJ, Gill DM: The life history of poly(ADP-ribose) in ADP-Ribosylations,
DNA repair and Cancer, M. Miwa et al. (Eds) Japan Sci. Soc. Press,
Tokyo/YNU Science Press, Utrecht, PP 129-140, 1983.
5.- Dang AQ, Faas FH, Carter WJ: Effects of
streptozotocin-induced diabetes on microsomal long-chain acyl-CoA
synthetase and hydrolase. Lipids 19: 578-582, 1984.
6.- Dang AQ, Faas FH, Carter WJ: Effects of
streptozotocin-induced diabetes on glycerophospholipid metabolism of the
rat liver. Lipids 19: 738-748, 1984.
7.- Dang AQ, Faas FH, Carter WJ: Influence of hypo- and
hyperthyroidism on rat liver glycerophospholipid metabolism. Lipids 20:
897-902, 1985.
8.- Faas FH, Dang AQ, Carter WJ: Regulation of rat liver
glycerophospholipid fatty acid composition in hypo- and hyperthyroidism.
In: Frontiers in Thyroidology, Vol I. (Medeiros-Neto G, Gaitan E,
eds) Plenum Medical book Company: New York, 1986, pp 681-684.
9.- Degges RD, Foster ME, DAng AQ, Read RC: Pulmonary
hypertensive effect of heparin protamine interaction: Evidence for
thromboxane B2 release from the lung itself. Am J Surg 154:
696-699, 1987.
10.- Faas FH, Dang AQ, Kemp K, Norman J, Carter WJ: Red
blood cell and plasma fatty acid composition in diabetes mellitus.
Metabolism 37: 711-713, 1988.
11.- Dang AQ, Faas FH, Lee JA, CArter WJ: Altered fatty
acid composition in plasma red blood cells, platelets and aorta of the
streptozotocin-induced diabetic rat. Metabolism 37: 1065-1072, 1988.
12.- Dang AQ, Faas FH, Carter WJ: Effects of hypo- and
hyperthyroidism on hepatic long-chain fatty acyl-CoA synthetase and
hydrolase. Hormone and Metabolic Res 21: 359-361, 1989.
13.- Dang AQ, Kemp K, Faas FH, Carter WJ: Effects of
dietary fats on fatty acid composition and Δ5 desaturase in
normal and diabetic rats. Lipids 24: 882-889, 1989.
14.- Carter WJ, Dang AQ, Faas FH, Lynch ME: Effects of
Clenbuterol on skeletal muscle mass, body composition and recovery from
surgical stress in senescent rats. Metabolism 40: 855-860, 1991.
15.- Dang AQ, Faas FH, Jethmalani S, Carter WJ: Decreased
incorporation of long chain fatty acids into red blood cell
phospholipids of streptozotocin-induced diabetic rats. Diabetes 40:
1645-1651, 1991.
16.-
Dang AQ, Faas FH, Jethmalani SM, Carter WJ: Modifications of platelet
phospholipid fatty acid composition in streptozocin-induced diabetic
rats. Prostaglandins Leukotrienes and Essential Fatty Acids 47:17-22,
1992.
17.-
Taylor BJ, Sziszak TL, Sziszak TJ, Dang AQ: Effects of alveolar hypoxia
on the mechanics after cromolyn sodium and U-60,257 in lambs J.
Developmental Physiology 18:73-80, 1992 .
19.-
Faas FH, Dang AQ, Hong XM, Schutz M, Luckert PH, Pollard M: Increased
Phospholipid Fatty Acid Remodeling In Human and Rat Prostatic
Adenocarcinoma Tissues. J. Urology 156:243-248, 1996.
.
20.- Klimberg VS, Kornbluth J, Cao Y, Dang
A, Blossom S, and Schaeffer RF: Glutamine suppresses PGE2
synthesis in breast cancer. J Surgical Res 63:293-297, 1996.
21. Faas FH, Dang AQ, White J, Schaefer R, Johnson
D.Increased prostatic lysophosphatidylcholine acyltransferase activity
in human prostate cancer: a marker for malignancy J Urol 165:463-468
2001
22. Smith WG, Wang J, Dang A, Reeves C, Bibbs D, Faas FH
: Lipoprotein susceptibility to oxidation in the macromolecular fraction
of plasma: relation to plasma lipids and oleate/linoleate ratio in
comparison with whole plasma in hypertriglyceridemia . Clin Chim Acta
316:11-7. 2002.
23. Smith WG, Wang J, Dang A, Reeves C, Bibbs D, Faas
FH: Gemfibrozil lowers plasma lipids and increases polyunsaturated
fatty acid content and oxidative susceptibility of lipoproteins in
hypertriglyceridemia. Submitted to Clin Chim Acta. April, 2002.
24. Faas FH, Dang A.Q, White, J. Schaefer RF, and Johnson
DE: Decreased prostatic arachidonic acid in human prostatic carcinoma.
BJU International 92:551-553, 2003.
25. Dang, A.Q , Faas, F.H, Mehta, R, White, J.,
and Dang, M.D: Characteristics of elevated
lysolecithin acyltransferase in human prostatic
cancer. Manuscript In Preparation.
26.An Q. Dang, Zhangping Peng, and William J.
Arendshorst. The Relative Abundance of Phospholipase C Isoforms In
Renal Cortical Microcirculation. Manuscript In Preparation.
27. John O. Nyalala, Jiang Wang, An Dang, Fred H. Faas
and W. Grady Smith. Hypertriglyceridemia and
Hypercholesterolemia: Group Comparisons of Fatty Acid Composition of
Lipids and Membranes and Effects of Drug Treatment . Submitted to
Experimental Biology and Medicine, Nov. 2005.
28. Zhangping Peng, An Dang, and William J. Arendshorst.
Age-Dependent Changes in Phospholipase C- Isozymes in
Preglomerular Resistance Arterioles, Glomeruli, and Aorta of
Wistar-Kyoto and Spontaneously Hypertensive Rats. Accepted
to be published in J. Hypertension, August, 2006.
